Instrumentation expertise is a field that generally characterizes physics engineering science in Indonesia. This area of expertise is based on the “instrumentation systems technology” approach. In this systemic approach, an understanding of the physical phenomena involved in a process that is handled and the way it is sensed is the scientific core of the physics engineering study program that bridges physics and engineering. The scientific fields needed in developing instrumentation system expertise include multi-physical processes, control systems, and interface systems. The courses offered to strengthen instrumentation systems engineering expertise are aligned with the scientific field.